Editing Littlefoot's Adventures of Osmosis Jones (section)

==Plot==
Frank DeTorre is an unkempt and slovenly zookeeper at the Sucat Memorial Zoo in Rhode Island. Depressed by the loss of his wife, he copes by overeating and foregoing basic hygiene, much to the concern of his daughter, Shane. Inside his body, which is called the "City of Frank" by its anthropomorphic inhabitants, white blood cell Osmosis "Ozzy" Jones is an overzealous officer of the Frank Police Department, the city's center for responses against bodily threats. He was demoted to patrol duty in the mouth after causing Frank to vomit on Shane's teacher Mrs. Boyd, due to Frank eating an oyster contaminated with some infectious bacteria, against orders, which led to Frank being fired from his previous job and banned from visiting Shane's school due to a restraining order filed by Mrs. Boyd.

A few years later, facing a serious challenge to his re-election prospects, Mayor Phlegmming doubles down on his junk food policies, ignoring their effect on Frank's health. This causes Frank to eat a boiled egg that stumbles into a chimpanzee's habitat, allowing Thrax, a deadly virusknown as "The Red Death", to enter his body. Phlegmming instructs Frank to take a cold pill through brain signals. The pill, Drixenol "Drix" Koldreliff, proceeds to disinfect the throat, covering up evidence of Thrax's arrival. Ozzy is told to assist Drix in his investigation, much to his displeasure. Thrax assumes leadership of a gang of sweat germs and launches an attack on Frank's nose, nearly killing Drix before Ozzy rescues him.

The duo pay a visit to Chill, a flu vaccine and one of Ozzy's informants, who directs them to Thrax's hideout in a germ-ridden nightclub in a large zit on Frank's forehead. Ozzy goes undercover and infiltrates Thrax's gang, where he learns that Thrax, wanting infamy as the deadliest virus in medical history, intends to masquerade as a common cold and use his knowledge of DNA to kill Frank within forty-eight hours. When Ozzy is discovered, Drix comes to his aid, causing a brawl which culminates in the zit being popped by a grenade. Its pus lands on Mrs. Boyd's lip during a meeting with her and Frank, foiling Frank's chance to apologize to her. In response, Phlegmming furiously closes the investigation, having Ozzy fired from the force and ordering Drix to leave Frank's body after reminding the latter that his services are only temporary.

Unbeknownst to the duo, Thrax has survived the zit's destruction and, after killing his remaining henchmen, proceeds to launch a lone assault on the hypothalamus where he steals a crucial nucleotide. He then abducts Phlegmming's secretary, Leah Estrogen, and flees to the mouth to escape. His actions disable the body's ability to regulate temperature and cause Frank to develop a dangerous fever. As Frank is taken to the hospital, Ozzy, having discovered Thrax's survival, reunites with Drix and convinces him not to leave. The two catch up to Thrax in the uvulaand rescue Leah. Thrax uses pollen to induce Frank to sneeze himself out of his mouth. Drix then shoots Ozzy after him and they land on Shane's cornea. As they fight, they end up on one of Shane's false eyelashes. Ozzy tricks Thrax into getting his hand embedded in the lash and escapes just as it falls into a beaker of rubbing alcohol, where Thrax dissolves.

As Frank's temperature surpasses 108 degrees, he goes into cardiac arrest. Riding on one of Shane's tears as she mourns her father, Ozzy returns to Frank's body with the stolen nucleotide, reviving him just in time. Ozzy is then welcomed back into the police force as he begins a relationship with Leah and Drix stays as Ozzy's new partner. Having narrowly cheated death, Frank commits himself to living a healthier lifestyle, which results in Phlegmming being removed from office and his opponent, Tom Colonic, replacing him. Phlegmming is reduced to janitorial duty in the bowels, where he accidentally ejects himself from Frank's body by triggering his flatulence.